Overview
2-Indanone is an aromatic ketone with the molecular formula C9H8O. It is a versatile intermediate in organic synthesis, particularly in the production of pharmaceuticals, fragrances, and agrochemicals. The compound is characterized by its colorless to pale yellow crystalline appearance and mild aromatic odor. 2-Indanone is derived from indane, a bicyclic hydrocarbon, and is commonly used in the synthesis of complex molecules due to its reactive ketone group. Its stability and solubility in organic solvents make it a preferred choice for various industrial applications.
Physical and Chemical Properties
2-Indanone exhibits typical ketone properties, including reactivity with nucleophiles and reducing agents. It has a melting point of 42-45 °C and a boiling point of 243-245 °C. The compound is soluble in common organic solvents such as ethanol, acetone, and ether but has limited solubility in water. Its density is approximately 1.09 g/cm³, and it is stable under normal conditions. However, it should be stored away from strong oxidizing agents to prevent hazardous reactions. The aromatic ring in 2-indanone contributes to its stability and reactivity in electrophilic substitution reactions.
Main Applications
2-Indanone is primarily used as an intermediate in the synthesis of pharmaceuticals, including antihypertensive and anti-inflammatory drugs. Its ketone group allows for further functionalization, making it valuable in medicinal chemistry. In the fragrance industry, 2-indanone is employed to create musky and woody notes. It also serves as a building block for agrochemicals, such as pesticides and herbicides, due to its ability to form derivatives with biological activity.
Safety and Storage
2-Indanone is classified as an irritant and can cause skin and eye irritation upon contact. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when handling the compound. Inhalation or ingestion should be avoided. Storage conditions should include a cool, dry, and well-ventilated area, away from heat sources and open flames. Containers must be tightly sealed to prevent moisture absorption and contamination. In case of spillage, absorb with inert material and dispose of according to local regulations.
B2B Procurement Guide
When procuring 2-indanone, verify the CAS number (615-13-4) and purity specifications to ensure quality. Reputable suppliers should provide safety data sheets (SDS) and certificates of analysis (CoA). Prices typically range from $50 to $100 per kilogram, depending on purity and order volume. Bulk purchases may qualify for discounts. Consider suppliers with reliable logistics and compliance with international safety standards, such as REACH or GHS.
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