Overview
2-Hydroxyacetamide, also known as glycolamide, is an organic compound with the molecular formula C2H5NO2. It is a white crystalline powder commonly used in pharmaceutical and chemical industries. The compound is derived from the reaction of glycolic acid with ammonia, and it serves as a versatile intermediate in organic synthesis. Due to its hydroxyl and amide functional groups, 2-hydroxyacetamide is reactive and can participate in various chemical reactions. Its stability and solubility in water and ethanol make it a preferred choice for laboratory and industrial applications.
Physical and Chemical Properties
2-Hydroxyacetamide is characterized by its white crystalline appearance and hygroscopic nature. It has a melting point of approximately 90-92°C and is soluble in water and ethanol. The compound is stable under normal conditions but should be stored away from moisture to prevent clumping. The molecular weight of 2-hydroxyacetamide is 75.07 g/mol, and its structure includes both hydroxyl and amide groups, which contribute to its reactivity. These properties make it suitable for use in various chemical processes, including the synthesis of more complex organic molecules.
Main Applications
2-Hydroxyacetamide is primarily used as an intermediate in the pharmaceutical industry. It is involved in the synthesis of active pharmaceutical ingredients (APIs) and other medicinal compounds. The compound's reactivity allows it to be incorporated into larger molecules with therapeutic properties. In addition to pharmaceuticals, 2-hydroxyacetamide is used in organic synthesis for producing specialty chemicals. Its ability to act as a building block in chemical reactions makes it valuable for researchers and industrial chemists alike.
Safety and Storage
When handling 2-hydroxyacetamide, it is essential to follow safety protocols to avoid exposure. The compound can cause irritation to the skin, eyes, and respiratory system. Personal protective equipment, such as gloves and goggles, should be worn during handling. Storage conditions for 2-hydroxyacetamide include keeping it in a cool, dry place away from direct sunlight. The compound should be sealed in airtight containers to prevent moisture absorption, which can affect its quality and reactivity.
B2B Procurement Guide
For B2B buyers, sourcing high-quality 2-hydroxyacetamide requires attention to purity and supplier reliability. The compound is typically available in varying purity grades, with pharmaceutical-grade being the highest. Buyers should request certificates of analysis (CoA) to verify the product's specifications. Price ranges for 2-hydroxyacetamide depend on purity and order quantity. Bulk purchases often come with discounts, but buyers should ensure that the supplier adheres to industry standards. Reputable suppliers will provide detailed product information and safety data sheets (SDS) upon request.
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