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2-Hydrazinopyridine

Updated: 2026-07-31

Overview

2-Hydrazinopyridine is an organic compound belonging to the class of hydrazine derivatives. It is widely utilized in synthetic chemistry due to its ability to form various heterocyclic structures. The compound is particularly valued in pharmaceutical research for its role in creating intermediates for drug development. Its molecular structure, featuring a pyridine ring with a hydrazine substituent, makes it a versatile building block in organic synthesis. Researchers and industrial chemists often employ it in reactions requiring nucleophilic hydrazine groups.

Physical and Chemical Properties

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2-Hydrazinopyridine appears as a white to pale yellow crystalline powder with a molecular weight of 109.13 g/mol. It is soluble in water and common organic solvents such as ethanol and methanol, which facilitates its use in various chemical reactions. The compound has a melting point range of approximately 80-85°C. Its stability under normal conditions makes it suitable for laboratory and industrial applications, though it should be protected from prolonged exposure to moisture and light to prevent degradation.

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Main Applications

In the pharmaceutical industry, 2-Hydrazinopyridine serves as a key intermediate in the synthesis of drugs, particularly those targeting central nervous system disorders. Its ability to form heterocyclic compounds is exploited in the development of novel therapeutic agents. Beyond pharmaceuticals, it finds use in agrochemicals for creating pesticides and herbicides. Additionally, it acts as a ligand in coordination chemistry, forming complexes with transition metals for catalytic applications.

Safety and Storage

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2-Hydrazinopyridine requires careful handling due to its potential to cause skin and eye irritation. Laboratory personnel should wear gloves, goggles, and protective clothing when working with this compound. Adequate ventilation is recommended to avoid inhalation of dust. For storage, keep the compound in a tightly sealed container in a cool, dry place, away from direct sunlight and moisture. Proper labeling and segregation from incompatible substances are essential to ensure safety and maintain product integrity.

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B2B Procurement Guide

When procuring 2-Hydrazinopyridine, B2B buyers should prioritize suppliers who provide detailed certificates of analysis (CoA) to confirm purity and composition. Bulk purchases often come with cost advantages, but it's crucial to assess storage capabilities to prevent degradation. Procurement professionals should also consider logistical factors, such as shipping conditions and lead times, to ensure timely delivery. Establishing long-term relationships with reputable suppliers can help secure consistent quality and favorable terms.

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