Overview
2-Ethoxy-4-nitropyridine is a chemical compound primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It belongs to the nitropyridine family, characterized by the presence of a nitro group and an ethoxy substituent on the pyridine ring. The compound is known for its reactivity, making it valuable in organic synthesis. Due to its specific molecular structure, 2-Ethoxy-4-nitropyridine is often employed in reactions that require the introduction of a nitro group into a heterocyclic framework. This property is particularly useful in the development of active pharmaceutical ingredients (APIs) and crop protection agents.
Physical and Chemical Properties
2-Ethoxy-4-nitropyridine typically appears as a pale yellow crystalline solid. It is soluble in common organic solvents such as ethanol, acetone, and dichloromethane, but has limited solubility in water. The compound is stable under normal storage conditions but may degrade when exposed to strong heat or prolonged light exposure. The molecular weight of 2-Ethoxy-4-nitropyridine is 168.15 g/mol, and its reactivity is influenced by the electron-withdrawing nitro group, which enhances its participation in nucleophilic substitution reactions. These properties make it a versatile intermediate in synthetic chemistry.
Main Applications
The primary use of 2-Ethoxy-4-nitropyridine is as a building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical industries. It serves as a precursor for the development of drugs targeting various therapeutic areas, including antimicrobial and anti-inflammatory agents. In agrochemical applications, the compound is utilized in the production of pesticides and herbicides. Its ability to act as an intermediate in the formation of nitrogen-containing heterocycles makes it valuable for creating compounds with biological activity against pests and weeds.
Safety and Storage
Handling 2-Ethoxy-4-nitropyridine requires adherence to standard safety protocols to minimize exposure risks. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. Proper ventilation is essential when working with the substance to prevent inhalation of dust or vapors. Personal protective equipment (PPE), including gloves, goggles, and lab coats, should be worn during handling. In case of skin contact, wash immediately with soap and water. Dispose of the compound in accordance with local regulations to avoid environmental contamination.
B2B Procurement Guide
When procuring 2-Ethoxy-4-nitropyridine, B2B buyers should prioritize suppliers with a proven track record of quality and regulatory compliance. Request certificates of analysis (CoA) to verify purity and consistency. Bulk purchasing may offer cost advantages, but ensure storage facilities meet the compound's requirements. Consider suppliers who provide technical support and documentation, such as material safety data sheets (MSDS). Establish clear communication channels to address any issues related to supply chain disruptions or quality deviations. Pricing is typically negotiated based on order volume and long-term contract agreements.
Related Manufacturers
- 主营：二苯胺、基嘧啶、甲苯氟、24滴、脱乙基、咯喹酮、嘧菌酯、溴苯基、氟磺隆、特戊醛、基哌嗪、氟苯基、碲化钠、酸性红、噻虫啉、双吡啶、三甘醇、异氯磷、茚草酮、吡啶醛、吡啶醇、二羧酸、三硫代碳酸钠、磷酸铁、聚酯多元醇
- 主营：硫酰胺、抗氧剂、氟苯基、2-戊酮酸、l-脯氨酰胺、l-苯基乳酸、l-氨基丙醇、d-苯基乳酸、2-甲基丁酸、2-甲基丁酯、3-氨基丙醇、2-氰基嘧啶、中间体、溴咪唑并、焦谷氨醇、异丁酰胺、利伐沙班、对氰基苯酚、邻氟苯甲酸、邻溴苯乙酸、间溴苯甲酸、丁位癸内酯
- 主营：三癸基铝、甲氧苯基、磺胺曲沙唑、17746-77-9、625392-06-5、1423716-55-5、1547041-34-8、8-二羟基萘、4-氯嘧啶盐酸盐、三十二烷基铝、甲氧基苯甲酸
- 主营：甘氨酸、溴化物、戊酸鈉、乙氧基、蒽甲酸、联吡啶、紫苏葶、锂电池、牛磺酸、褪黑素、磷酸铟、新癸酸、赖氨酸、溴化鏻、藏花醛、豆甾醇、羟乙基、维素酶、庚二酸、呋虫胺、丹参素、萘甲醛、槐豆胶、黄柏酮、元明粉
- 主营：正辛胺、柠檬酸、尿嘧啶、15397-15-6、119736-16-2、4-嘧啶酮、923289-21-8、152628-02-9、2346620-55-9、抗皱素、绿原酸、异丁基、三辛胺、双醚芴、姜黄素、角鲨烯、精磺胺、蒜氨酸、九甘醇、氟苯基、苯甲酰胺、比卡鲁胺、四氢嘧啶、氨基二环、麦角硫因
- 主营：甘氨酸、阻燃剂、胶黏剂、3282-24-4、乙氧基、2768-02-7、7377-08-4、4865-84-3、5471-63-6、2799-16-8、蒽甲酸、退除剂、中性红、肉桂醛、退镍液、阻燃毯、草酸铜、抛光盐、戊二酸、插入管、丙二胺、碳化硼、蓝钨粉、硫酸镝、二氨基