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2-Cyano-4-hydroxy2

Updated: 2026-07-23

Overview

2-Cyano-4-hydroxybenzoic acid is an organic compound with the molecular formula C8H5NO3. It is commonly used as an intermediate in pharmaceutical manufacturing and organic synthesis. The compound features both a cyano (-CN) and a hydroxyl (-OH) functional group, making it versatile for various chemical reactions. Its applications span across the production of active pharmaceutical ingredients (APIs) and specialty chemicals. Due to its reactivity, it is often handled under controlled conditions in industrial settings.

Physical and Chemical Properties

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2-Cyano-4-hydroxybenzoic acid typically appears as a white to off-white crystalline powder. It has a molecular weight of 163.13 g/mol and a melting point range of approximately 200-205°C. The compound is soluble in polar organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), but only slightly soluble in water. The presence of both cyano and hydroxyl groups contributes to its reactivity, particularly in nucleophilic substitution and condensation reactions. Stability is maintained under recommended storage conditions, but exposure to strong oxidizing agents should be avoided.

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Main Applications

This compound is primarily utilized in the pharmaceutical industry as an intermediate for synthesizing more complex molecules. Its functional groups allow for the creation of diverse chemical structures, making it valuable in drug development. Additionally, 2-cyano-4-hydroxybenzoic acid finds use in organic synthesis for producing dyes, agrochemicals, and other specialty chemicals. Its role in these processes underscores its importance in industrial chemistry.

Safety and Storage

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Proper handling of 2-cyano-4-hydroxybenzoic acid is essential to ensure safety. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. Containers must be tightly sealed to prevent contamination and degradation. Personal protective equipment (PPE), including gloves and safety goggles, should be worn when handling the substance. In case of exposure, immediate washing with plenty of water is recommended, and medical attention should be sought if necessary.

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B2B Procurement Guide

When procuring 2-cyano-4-hydroxybenzoic acid, B2B buyers should prioritize suppliers who adhere to stringent quality control measures. Certificates of analysis (CoA) and compliance with regulatory standards such as REACH or FDA guidelines are critical. Bulk purchasing may offer cost advantages, but buyers should verify storage and handling capabilities to maintain product integrity. Establishing long-term relationships with reputable suppliers can ensure consistent quality and reliable supply chains.

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