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2-Chlorobipyridine

Updated: 2026-07-21

Overview

2-Chlorobiphenyl, also known as o-chlorobiphenyl, is a chlorinated biphenyl compound with the molecular formula C12H9Cl. It is a colorless to pale yellow liquid with a characteristic aromatic odor. This compound is primarily used as a chemical intermediate in the synthesis of more complex organic compounds. As a member of the chlorinated biphenyl family, 2-chlorobiphenyl shares some structural similarities with polychlorinated biphenyls (PCBs), though it contains only one chlorine atom. Its relatively simple structure makes it useful for research purposes and as a building block in organic synthesis.

Physical and Chemical Properties

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2-Chlorobiphenyl is a stable compound under normal temperature and pressure conditions. It has a density of approximately 1.05 g/cm³ and boils at 285°C. The compound is insoluble in water but readily dissolves in most organic solvents, including ethanol, ether, and benzene. The presence of the chlorine atom at the ortho position influences the compound's reactivity and physical properties. Compared to biphenyl, the chlorine substitution increases the molecular weight and slightly alters the boiling point. The compound's stability makes it suitable for various chemical reactions where a chlorinated aromatic moiety is required.

Main Applications

The primary application of 2-chlorobiphenyl is as a chemical intermediate in organic synthesis. It serves as a building block for more complex molecules in pharmaceutical and agrochemical research. The compound's chlorinated aromatic structure makes it valuable for studying reaction mechanisms and developing new synthetic pathways. In research settings, 2-chlorobiphenyl is used to investigate the properties and behavior of chlorinated aromatic compounds. It may also find use in material science applications, particularly in the development of specialty polymers or as a model compound for environmental studies on chlorinated organic pollutants.

Safety and Storage

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2-Chlorobiphenyl requires careful handling due to its potential health hazards. The compound is harmful if inhaled or swallowed and can cause skin and eye irritation. Appropriate personal protective equipment, including gloves and safety goggles, should be worn when working with this chemical. Storage should be in a cool, dry, well-ventilated area away from heat sources and open flames. Containers should be tightly sealed to prevent evaporation and contamination. In case of spillage, absorb with inert material and dispose of according to local regulations. Proper ventilation is essential when handling this compound to avoid inhalation exposure.

B2B Procurement Guide

When procuring 2-chlorobiphenyl for industrial or research purposes, it's essential to verify the supplier's credentials and product specifications. Request a certificate of analysis (CoA) to confirm purity and identity. The compound is typically available in laboratory quantities ranging from grams to kilograms. Consider the intended application when selecting a grade, as purity requirements may vary. Technical grade may be sufficient for some industrial applications, while research purposes may require higher purity. Lead times can vary depending on supplier inventory, so plan purchases accordingly. Always ensure proper documentation for regulatory compliance, especially for international shipments.

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