Overview
2-Chlorophenol (2-CP) is a chlorinated derivative of phenol, classified as an aromatic organic compound. It is widely used in industrial chemistry due to its reactivity as an intermediate. The compound is synthesized through chlorination of phenol or hydrolysis of 1,2-dichlorobenzene. Its primary role lies in synthesizing higher-value chemicals, including pesticides like 2,4-D (a herbicide) and pharmaceuticals. The global demand for 2-CP is driven by agrochemical and pharmaceutical industries, with Asia being a major production hub.
Physical and Chemical Properties
2-Chlorophenol is a volatile liquid with a sharp, medicinal odor. It exhibits moderate solubility in water (2.5 g/L at 20°C) but is highly soluble in alcohols, ethers, and benzene. The chlorine substituent at the ortho position increases its acidity compared to phenol (pKa ≈ 8.5). The compound is thermally stable but decomposes under strong oxidizing conditions, releasing toxic fumes (hydrogen chloride, carbon monoxide). Its density (1.24 g/cm³) and boiling point (174.9°C) make it suitable for distillation purification in industrial settings.
Main Applications
In agrochemicals, 2-CP is a precursor for herbicides like 2,4-dichlorophenoxyacetic acid (2,4-D). It also serves in dye manufacturing, producing intermediates for azo dyes. The pharmaceutical industry uses it to synthesize antiseptics and antipyretics. Additionally, 2-CP finds niche applications in disinfectants and preservatives due to its biocidal properties. Its derivatives are employed in rubber chemicals and flame retardants, though these uses are declining due to environmental regulations.
Safety and Storage
2-Chlorophenol is toxic (LD50 oral rat: 670 mg/kg) and corrosive, requiring strict handling protocols. Use chemical-resistant gloves (nitrile or neoprene), goggles, and fume hoods to avoid skin/eye contact or inhalation. Spills should be neutralized with sodium carbonate and absorbed in inert material. Store in stainless steel or polyethylene containers, away from heat and oxidizers. Shelf life is typically 2 years under recommended conditions. Regulatory compliance (e.g., OSHA Hazard Communication Standard) is mandatory for workplace safety.
B2B Procurement Guide
When sourcing 2-CP, prioritize suppliers with GMP or ISO 9001 certification. Key specifications include purity (≥98%), water content (<0.5%), and absence of heavy metals. Bulk buyers should negotiate for drum (200 kg) or IBC tank options to reduce costs. Logistics require UN-certified packaging (UN 2021, Class 6.1) for hazardous materials. Spot prices fluctuate with chlorine and phenol feedstock markets; long-term contracts are advisable for stable supply chains. Always request SDS and CoA documentation before purchase.
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