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2-Aminoadipic acid

Updated: 2026-08-10

Overview

2-Aminoadipic acid is an organic compound classified as an amino acid derivative. It plays a significant role in lysine metabolism and is often used in biochemical research. The compound exists as a white crystalline powder and is soluble in water. Its molecular structure includes both amino and carboxyl functional groups, making it useful in various chemical and biological applications. As an intermediate in metabolic pathways, 2-aminoadipic acid is studied for its role in neurological and metabolic disorders. It is also utilized in pharmaceutical synthesis, particularly in the development of drugs targeting amino acid metabolism.

Physical and Chemical Properties

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2-Aminoadipic acid has a molecular weight of 161.16 g/mol and typically appears as a white crystalline solid. It decomposes at temperatures around 210-215°C, and its solubility in water makes it suitable for aqueous-based applications. The compound is slightly soluble in ethanol but insoluble in non-polar solvents. Its chiral nature allows it to exist in both D- and L-forms, though the racemic mixture (DL-form) is commonly available. The presence of both amino and carboxyl groups enables it to participate in various chemical reactions, including peptide bond formation and esterification.

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Main Applications

2-Aminoadipic acid is primarily used in biochemical research, particularly in studies related to lysine metabolism and neurological disorders. It serves as a precursor in the synthesis of other bioactive compounds and is investigated for its potential role in metabolic pathways. In the pharmaceutical industry, it is employed as an intermediate in drug development, especially for medications targeting amino acid-related conditions. Additionally, its applications extend to nutritional research and the study of metabolic diseases.

Safety and Storage

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When handling 2-aminoadipic acid, it is essential to use appropriate personal protective equipment, including gloves and safety goggles, to avoid skin or eye contact. Inhalation of dust should be prevented by working in a well-ventilated area or using a fume hood. Storage conditions should include a cool, dry environment away from direct light and moisture. The compound should be kept in a tightly sealed container to maintain its stability and prevent degradation. Proper disposal methods should be followed in accordance with local regulations.

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B2B Procurement Guide

When procuring 2-aminoadipic acid, buyers should specify purity requirements, typically ≥98%, and request analytical certificates from suppliers. Pricing varies based on purity and quantity, with bulk orders often receiving discounts. It is advisable to source from reputable suppliers with a track record in fine chemicals. Consider logistical factors such as shipping conditions and lead times, especially for international orders. Buyers should also verify compliance with regional regulations regarding the import and use of chemical substances.

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