Overview
2-Adamantanone is a ketone derivative of adamantane, characterized by its unique cage-like molecular structure. This compound is primarily utilized in the pharmaceutical industry as an intermediate for synthesizing various drugs. Its rigid structure and stability make it valuable in organic chemistry and material science. Due to its high purity requirements, 2-adamantanone is typically produced under controlled laboratory conditions. It is commonly supplied in crystalline form, ensuring ease of handling and storage for industrial applications.
Physical and Chemical Properties
2-Adamantanone is a white crystalline solid with a melting point ranging between 240-245°C. It exhibits high thermal stability, making it suitable for high-temperature applications. The compound is soluble in common organic solvents like ethanol and acetone but remains insoluble in water. Its molecular structure, featuring a tricyclo[3.3.1.1³,⁷]decane framework, contributes to its rigidity and chemical inertness. These properties are advantageous in synthetic chemistry, where stability and predictable reactivity are crucial.
Main Applications
The primary use of 2-adamantanone is as a pharmaceutical intermediate, particularly in the synthesis of antiviral and neurological drugs. Its unique structure allows for the creation of complex molecules with enhanced bioavailability. Additionally, it serves as a building block in organic synthesis for producing specialty chemicals and polymer additives. Researchers also explore its potential in material science for developing advanced polymers with high thermal resistance.
Safety and Storage
2-Adamantanone should be handled with appropriate personal protective equipment, including gloves and safety goggles, to prevent skin contact or eye irritation. Although it is not highly toxic, inhalation or ingestion should be avoided. Storage conditions require a cool, dry environment away from direct sunlight and moisture. Properly sealed containers are recommended to maintain purity and prevent degradation over time.
B2B Procurement Guide
When procuring 2-adamantanone, buyers should verify the CAS number (700-58-3) to ensure product authenticity. Purity specifications, typically ranging from 98% to 99.5%, should be confirmed based on intended use. Bulk purchases often qualify for discounts, so inquire about volume pricing. Reliable suppliers should provide material safety data sheets (MSDS) and certificates of analysis (CoA) to guarantee quality and compliance with industry standards.
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