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2-Acrylamide

Updated: 2026-07-15

Overview

2-Acrylamide (C3H5NO) is a white crystalline solid primarily used in industrial applications such as polymer synthesis and water treatment. Its high reactivity makes it a key monomer in producing polyacrylamides, which are widely used in various sectors. This compound is synthesized from acrylonitrile through hydrolysis and is known for its toxicity, requiring careful handling. Its versatility in forming copolymers and hydrogels has expanded its use in biotechnology and medical fields.

Physical and Chemical Properties

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2-Acrylamide is highly soluble in water, ethanol, and acetone, with a melting point of 84-86 °C. It decomposes at 125 °C, releasing toxic fumes. The compound’s density is 1.13 g/cm³, and it exhibits high reactivity due to its vinyl group. Its ability to polymerize under heat or light makes it valuable in industrial processes. However, this property also necessitates strict storage conditions to prevent unintended polymerization, which can be hazardous.

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Main Applications

The primary use of 2-acrylamide is in the production of polyacrylamides, which serve as flocculants in water treatment and soil conditioning. It is also used in papermaking to improve strength and retention. In the adhesive industry, 2-acrylamide enhances bonding properties. Additionally, its role in gel electrophoresis and drug delivery systems highlights its importance in biotechnology and pharmaceuticals.

Safety and Storage

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2-Acrylamide is classified as a neurotoxin and potential carcinogen. Proper handling includes using gloves, goggles, and respiratory protection. Storage should be in a cool, dry place, away from oxidizing agents and direct sunlight. Spills must be contained and cleaned immediately with appropriate absorbents. Disposal should comply with local regulations to minimize environmental impact.

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B2B Procurement Guide

When procuring 2-acrylamide, verify the supplier’s certification and purity levels (typically 99% or higher). Bulk purchases may offer cost savings, but ensure proper storage facilities are available. Request Material Safety Data Sheets (MSDS) and confirm compliance with international safety standards such as REACH or OSHA. Consider logistics for safe transportation, especially for large quantities.

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