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2-(4-Nitrophenyl)ethanol

Updated: 2026-08-28

Overview

2-(4-Nitrophenyl)ethanol is an organic compound with the molecular formula C8H9NO3. It is a derivative of ethanol with a nitro group attached to the phenyl ring. This compound is widely used in the pharmaceutical and chemical industries as an intermediate for synthesizing more complex molecules. Its pale yellow crystalline appearance and moderate solubility in organic solvents make it suitable for various laboratory and industrial applications. The compound is typically synthesized through nitration or other organic reactions involving phenethyl alcohol.

Physical and Chemical Properties

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2-(4-Nitrophenyl)ethanol is a stable compound under normal conditions, with a melting point around 90-92°C. It is soluble in common organic solvents like ethanol and methanol but has limited solubility in water. The presence of the nitro group enhances its reactivity in certain chemical reactions. The compound exhibits typical aromatic and alcohol functional group behaviors, making it versatile for further chemical modifications. Its stability and predictable reactivity profile are key reasons for its widespread use in synthetic chemistry.

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Main Applications

This compound is primarily used as an intermediate in the synthesis of pharmaceuticals, dyes, and other fine chemicals. It serves as a building block for more complex molecules, particularly in the production of active pharmaceutical ingredients (APIs). In addition to pharmaceutical applications, 2-(4-Nitrophenyl)ethanol is also utilized in research laboratories for studying nitroaromatic compounds and their reactions. Its role in organic synthesis is well-documented, making it a valuable reagent for chemists.

Safety and Storage

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Proper handling of 2-(4-Nitrophenyl)ethanol requires adherence to safety protocols. The compound should be stored in a cool, dry place, away from strong oxidizing agents and direct sunlight. Exposure to moisture should be minimized to prevent degradation. Personal protective equipment (PPE), including gloves and safety goggles, is recommended when handling this chemical. In case of skin contact or inhalation, immediate washing or fresh air exposure is advised. Always consult the material safety data sheet (MSDS) for detailed safety information.

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B2B Procurement Guide

When procuring 2-(4-Nitrophenyl)ethanol, it is essential to verify the purity and quality of the product. Suppliers should provide a certificate of analysis (CoA) to confirm the compound's specifications. Packaging should be airtight and labeled clearly with hazard information. Bulk purchases may offer cost savings, but storage conditions must be carefully managed. Establish a reliable supply chain to ensure consistent quality and availability. Comparing prices and lead times from multiple suppliers can help optimize procurement strategies.

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