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2-(4'-Methylphenyl)propionic acid

Updated: 2026-07-24

Overview

2-(4'-Methylphenyl)propanoic acid is an organic compound belonging to the class of aromatic carboxylic acids. It is commonly used as an intermediate in pharmaceutical synthesis and chemical research. The compound features a methyl group attached to a phenyl ring, which is further connected to a propanoic acid moiety. This structure makes it valuable for various synthetic applications. Due to its role as a building block in organic chemistry, 2-(4'-Methylphenyl)propanoic acid is often utilized in the production of more complex molecules. Its stability and reactivity under controlled conditions make it a preferred choice for laboratories and industrial processes.

Physical and Chemical Properties

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2-(4'-Methylphenyl)propanoic acid typically appears as a white to off-white crystalline powder. It has a molecular weight of 164.20 g/mol and a melting point around 100-102°C. The compound is soluble in common organic solvents such as ethanol and methanol but has limited solubility in water. The presence of the carboxylic acid group in its structure allows it to participate in various chemical reactions, including esterification and amidation. The methyl group on the phenyl ring can influence the compound's electronic properties, making it useful in tailored synthetic pathways.

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Main Applications

This compound is primarily used as an intermediate in the pharmaceutical industry, where it serves as a precursor for active pharmaceutical ingredients (APIs). Its structure is amenable to further functionalization, enabling the synthesis of diverse drug molecules. Additionally, 2-(4'-Methylphenyl)propanoic acid finds applications in chemical research and development. It is employed in the synthesis of specialty chemicals, fragrances, and agrochemicals. Its versatility makes it a valuable component in laboratory settings and industrial-scale production.

Safety and Storage

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Proper handling of 2-(4'-Methylphenyl)propanoic acid is essential to ensure safety. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. Containers must be tightly sealed to prevent contamination or degradation. Personal protective equipment (PPE), including gloves and goggles, should be worn when handling the compound. Inhalation or skin contact should be avoided, as it may cause irritation. In case of exposure, rinse thoroughly with water and seek medical attention if necessary.

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B2B Procurement Guide

When procuring 2-(4'-Methylphenyl)propanoic acid, it is crucial to verify the CAS number (938-94-3) to ensure the correct product. Buyers should assess the purity level required for their specific application, as higher purity grades may be necessary for pharmaceutical use. Suppliers should provide detailed technical data sheets (TDS) and certificates of analysis (CoA). Comparing prices from multiple vendors and checking for bulk purchase discounts can help optimize procurement costs. Establishing long-term relationships with reliable suppliers ensures consistent quality and availability.

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