Overview
2-(4-Chlorophenylthio)nicotinic Acid is a specialized organic compound primarily used in the synthesis of pharmaceuticals and agrochemicals. Its molecular structure includes a chlorophenylthio group attached to a nicotinic acid moiety, which contributes to its reactivity and utility in various chemical reactions. This compound is typically synthesized through controlled chemical reactions involving chlorophenyl derivatives and nicotinic acid precursors. Its applications are predominantly in research and industrial settings, where it serves as a key intermediate in the development of more complex molecules.
Physical and Chemical Properties
2-(4-Chlorophenylthio)nicotinic Acid is a white to off-white crystalline powder with a molecular weight of approximately 265.72 g/mol. It is soluble in common organic solvents such as methanol, ethanol, and DMSO, but has limited solubility in water. The compound is stable under normal storage conditions but should be protected from prolonged exposure to light and moisture to prevent degradation. Its exact melting and boiling points are not widely documented, but it is known to decompose at higher temperatures.
Main Applications
The primary use of 2-(4-Chlorophenylthio)nicotinic Acid is as an intermediate in the pharmaceutical industry, where it is utilized in the synthesis of active pharmaceutical ingredients (APIs). It is also employed in agrochemical research for the development of pesticides and herbicides. Due to its specific chemical structure, this compound is valued for its ability to introduce the chlorophenylthio group into larger molecules, thereby modifying their biological activity or physical properties.
Safety and Storage
Handling 2-(4-Chlorophenylthio)nicotinic Acid requires standard laboratory safety precautions. Personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn to avoid skin contact or inhalation of dust. The compound should be stored in a tightly sealed container in a cool, dry place, away from direct sunlight and moisture. Proper ventilation is recommended when working with this chemical to minimize exposure to airborne particles.
B2B Procurement Guide
When procuring 2-(4-Chlorophenylthio)nicotinic Acid, buyers should prioritize suppliers with a proven track record of providing high-purity chemicals. It is advisable to request certificates of analysis (CoA) to verify the compound's purity and consistency. Bulk purchases may offer cost advantages, but storage conditions must be carefully managed to maintain product integrity. Buyers should also consider lead times and shipping conditions to ensure the chemical arrives in optimal condition.
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