Overview
2-(2-Chlorophenyl)ethylamine is an organic compound primarily used in pharmaceutical and chemical synthesis. It belongs to the class of phenethylamines and is characterized by the presence of a chlorine atom on the benzene ring. This compound is a valuable intermediate in the production of various drugs and specialty chemicals. The synthesis of 2-(2-Chlorophenyl)ethylamine involves multi-step organic reactions, often starting from 2-chlorobenzaldehyde or similar precursors. Due to its reactivity, it is commonly used in research laboratories and industrial settings where fine chemicals are produced.
Physical and Chemical Properties
2-(2-Chlorophenyl)ethylamine is a colorless to pale yellow liquid at room temperature. It has a molecular weight of 155.62 g/mol and a density of approximately 1.12 g/cm³. The compound is soluble in common organic solvents such as ethanol, ether, and dichloromethane but has limited solubility in water. Key chemical properties include its amine group, which makes it reactive in various organic reactions, and the chlorine substituent, which influences its electronic and steric characteristics. These properties make it useful in synthetic chemistry, particularly in the formation of more complex molecules.
Main Applications
The primary application of 2-(2-Chlorophenyl)ethylamine is in the pharmaceutical industry, where it serves as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is used in the production of drugs targeting the central nervous system, among others. Additionally, this compound finds use in chemical research as a building block for more complex molecules. Its reactivity allows for modifications that can lead to the development of new compounds with potential therapeutic or industrial applications.
Safety and Storage
2-(2-Chlorophenyl)ethylamine is classified as an irritant and should be handled with care. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when working with this compound. Inhalation or skin contact should be avoided to prevent irritation or other adverse effects. Storage should be in a cool, dry place away from light and moisture to maintain stability. The compound should be kept in tightly sealed containers to prevent contamination or degradation. In case of spills, appropriate cleanup procedures should be followed to ensure safety.
B2B Procurement Guide
When procuring 2-(2-Chlorophenyl)ethylamine, it is essential to verify the CAS number (19883-74-0) to ensure the correct compound is being purchased. Purity is another critical factor, as impurities can affect the outcome of synthetic processes. Reputable suppliers should provide certificates of analysis (CoA) to confirm the product's specifications. Prices can vary significantly based on purity and quantity, with common ranges between $50 and $200 per gram for laboratory-scale quantities. Bulk purchases may offer cost savings. It is advisable to establish relationships with reliable suppliers to ensure consistent quality and availability.
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