Overview
1,4-Dioxane is a heterocyclic organic compound widely used as a solvent in various industrial and laboratory applications. It is a colorless liquid with a faint sweet odor and is miscible with water and most organic solvents. Due to its solvent properties, it is commonly employed in the production of pharmaceuticals, cosmetics, and adhesives. However, its potential health risks, including carcinogenicity, necessitate careful handling and storage. First synthesized in the late 19th century, 1,4-dioxane has since become a staple in many chemical processes. Its ability to dissolve a wide range of substances makes it invaluable in laboratories and manufacturing. Despite its utility, regulatory agencies have imposed strict guidelines on its use due to environmental and health concerns.
Physical and Chemical Properties
1,4-Dioxane is characterized by its high solubility in water and organic solvents, making it an excellent solvent for various chemical reactions. It has a relatively low boiling point of 101.1 °C and a melting point of 11.8 °C. The compound is highly flammable and can form explosive peroxides upon prolonged exposure to air, necessitating the use of stabilizers in commercial products. The density of 1,4-dioxane is 1.033 g/cm³, and it exhibits a faint sweet odor. Its molecular structure consists of a six-membered ring with two oxygen atoms, contributing to its stability and solvent properties. However, this stability also means it can persist in the environment, leading to potential contamination issues.
Main Applications
1,4-Dioxane is primarily used as a solvent in the pharmaceutical industry for the synthesis of drugs and other medical compounds. It is also a common ingredient in cosmetics, where it helps dissolve other ingredients to create uniform products. Additionally, it is used in the production of adhesives, dyes, and laboratory reagents. In laboratories, 1,4-dioxane is valued for its ability to dissolve a wide range of organic and inorganic compounds. It is often used in extraction processes and as a reaction medium. Despite its versatility, its use is declining in some industries due to health and environmental concerns, with safer alternatives being explored.
Safety and Storage
Due to its flammability and potential to form explosive peroxides, 1,4-dioxane must be stored in a cool, well-ventilated area away from heat sources and open flames. Containers should be tightly sealed to prevent exposure to air, which can lead to peroxide formation. Stabilizers are often added to commercial products to mitigate this risk. Personal protective equipment, including gloves and goggles, should be worn when handling 1,4-dioxane. Inhalation and skin contact should be avoided, as the compound is a potential carcinogen. Spills should be cleaned up immediately using appropriate absorbent materials, and contaminated areas should be ventilated thoroughly.
B2B Procurement Guide
When procuring 1,4-dioxane, it is essential to verify the CAS number (123-91-1) to ensure product authenticity. Buyers should also check the purity level, which typically ranges from 99% to 99.9%, depending on the application. Supplier certifications, such as ISO or GMP, can provide additional assurance of quality. Storage and handling conditions should be confirmed with the supplier to ensure compliance with safety regulations. Bulk purchases may offer cost savings, but proper storage facilities must be available. Prices vary based on purity and quantity, with reference prices ranging from $10 to $20 per liter. Always consult safety data sheets (SDS) before use.
Related Manufacturers
- 主营：泰科继电器、电解电容、连接器、RY611005、宏发继电器、PCB端子、西霸士产品、RTS3T024、RT174024、RT424012、IM03GR、IM03TS、RE030005、PE014012、Dynamic连接器