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1,3,5-Trihydroxybenzene

Updated: 2026-08-04

Overview

Phloroglucinol anhydrous powder, chemically known as 1,3,5-trihydroxybenzene, is a versatile organic compound with significant applications in pharmaceuticals and chemical synthesis. It is derived from the hydrogenation of phloroglucinol and is commonly used as an intermediate in the production of dyes, resins, and pharmaceuticals. This compound is valued for its antispasmodic properties, making it a key ingredient in medications for gastrointestinal disorders. Its role as a reducing agent and its ability to form complexes with various metals also make it useful in analytical chemistry.

Physical and Chemical Properties

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Phloroglucinol anhydrous powder appears as a white to pale yellow crystalline solid with a molecular weight of 126.11 g/mol. It has a density of 1.46 g/cm³ and melts at 218-220 °C. The compound is highly soluble in water, ethanol, and ether, which facilitates its use in various chemical reactions. Its key chemical properties include its ability to act as a reducing agent and its reactivity with aldehydes and ketones to form flavones and other derivatives. These properties are exploited in organic synthesis and the production of dyes and pharmaceuticals.

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Main Applications

The primary use of phloroglucinol anhydrous powder is in the pharmaceutical industry, where it serves as an active ingredient in antispasmodic drugs. It is also used as an intermediate in the synthesis of dyes, particularly those used in textiles and inks. In addition, this compound finds applications in analytical chemistry as a reagent for detecting and quantifying various substances. Its role in organic synthesis includes the production of resins, plastics, and other specialty chemicals.

Safety and Storage

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Phloroglucinol anhydrous powder should be handled with care to avoid inhalation or skin contact, which can cause irritation. Appropriate personal protective equipment, such as gloves and goggles, should be used during handling. Storage conditions are critical to maintaining the compound's stability. It should be kept in a cool, dry place, away from direct sunlight and moisture. Properly sealed containers are recommended to prevent degradation and contamination.

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B2B Procurement Guide

When procuring phloroglucinol anhydrous powder, buyers should prioritize purity levels, typically ≥98%, to ensure optimal performance in applications. Supplier reliability and compliance with industry standards are also crucial factors. Packaging should be inspected for integrity, and bulk purchases may offer cost advantages. Buyers are advised to request certificates of analysis (CoA) and material safety data sheets (MSDS) to verify quality and safety specifications.

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