Overview
13-Hydroxybakuchiol is a bioactive compound derived from the seeds of Psoralea corylifolia, a plant traditionally used in Chinese medicine. It has gained significant attention in the cosmetics and pharmaceutical industries due to its potent antioxidant and anti-aging properties. Unlike its parent compound, bakuchiol, 13-Hydroxybakuchiol offers enhanced stability and efficacy, making it a preferred choice for advanced skincare formulations. Research has shown that 13-Hydroxybakuchiol can effectively inhibit melanin production, reducing hyperpigmentation and promoting an even skin tone. Additionally, it stimulates collagen synthesis, which helps in maintaining skin elasticity and reducing the appearance of fine lines and wrinkles. These properties make it a valuable ingredient in anti-aging and brightening skincare products.
Physical and Chemical Properties
13-Hydroxybakuchiol is characterized by its light yellow to white crystalline appearance and a molecular weight of 284.35 g/mol. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) but has limited solubility in water. The compound exhibits a melting point range of approximately 80-85°C, which is indicative of its stability under typical storage conditions. The molecular structure of 13-Hydroxybakuchiol includes a phenol group, which contributes to its antioxidant activity. This structure allows it to scavenge free radicals and protect skin cells from oxidative stress, a major contributor to aging. Its solubility profile makes it suitable for incorporation into various cosmetic formulations, including serums, creams, and lotions.
Main Applications
13-Hydroxybakuchiol is primarily used in the cosmetics industry, where it serves as a key ingredient in anti-aging and skin-brightening products. Its ability to inhibit melanin production makes it effective in treating hyperpigmentation, age spots, and uneven skin tone. Additionally, its collagen-boosting properties help in reducing the appearance of wrinkles and improving skin elasticity. In the pharmaceutical sector, 13-Hydroxybakuchiol is being explored for its potential therapeutic applications, including its anti-inflammatory and antimicrobial properties. Preliminary studies suggest that it may be beneficial in treating skin conditions such as acne and eczema. However, further research is needed to fully understand its pharmacological potential.
Safety and Storage
13-Hydroxybakuchiol is generally considered safe for topical use in cosmetic formulations. However, it is recommended to conduct patch tests before widespread application to ensure no allergic reactions occur. The compound should be stored in a cool, dry place, away from direct sunlight and moisture, to maintain its stability and efficacy. When handling 13-Hydroxybakuchiol in its pure form, appropriate personal protective equipment (PPE) such as gloves and safety glasses should be used to prevent skin and eye contact. In case of accidental exposure, rinse thoroughly with water and seek medical advice if irritation persists. Proper storage and handling are essential to preserve the compound's integrity and ensure optimal performance in end products.
B2B Procurement Guide
When procuring 13-Hydroxybakuchiol for industrial or commercial use, it is crucial to verify the supplier's credentials and request certificates of analysis (COA) to confirm the compound's purity and quality. The reference price range for 13-Hydroxybakuchiol varies between $50 and $200 per gram, depending on the supplier and the purity level required. Bulk purchases may qualify for discounts, but it is advisable to start with smaller quantities to assess the material's quality and compatibility with your formulations. Additionally, consider suppliers who offer technical support and can provide guidance on the optimal usage concentrations for different applications. Reliable procurement practices ensure consistency in product quality and performance.
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