Overview
1-Methylazepane, also known as N-Methylhexamethyleneimine, is a cyclic amine with a seven-membered ring structure. It is a versatile intermediate in organic synthesis, particularly in the pharmaceutical industry. The compound is characterized by its basic nitrogen atom and is commonly used in the synthesis of more complex molecules. Due to its volatility, 1-Methylazepane requires careful handling and storage. It is typically supplied as a colorless to pale yellow liquid, and its reactivity makes it valuable for various chemical transformations. The compound's CAS number is 931-35-1, and its molecular weight is 113.20 g/mol.
Physical and Chemical Properties
1-Methylazepane is a colorless to pale yellow liquid with a density of approximately 0.83 g/cm³. It has a boiling point of 142-144 °C at standard atmospheric pressure and is soluble in common organic solvents such as ethanol and ether. The compound's cyclic structure and basic nitrogen contribute to its reactivity. The molecular formula of 1-Methylazepane is C7H15N, and it exhibits typical amine properties, including the ability to form salts with acids. Its volatility and flammability necessitate proper storage and handling to prevent accidents. The compound should be kept away from oxidizing agents and stored in a cool, dry environment.
Main Applications
1-Methylazepane is primarily used as an intermediate in organic synthesis, particularly in the pharmaceutical industry. It serves as a building block for the preparation of more complex molecules, including active pharmaceutical ingredients (APIs). Its cyclic structure and basic nature make it useful in reactions requiring amine functionality. In addition to pharmaceuticals, 1-Methylazepane finds applications in agrochemicals and specialty chemicals. Its reactivity allows for the introduction of the azepane ring into various compounds, enhancing their biological or chemical properties. The compound's versatility makes it a valuable tool for chemists in research and industrial settings.
Safety and Storage
1-Methylazepane is a flammable liquid and should be handled with care. It is an irritant to skin and eyes, and proper personal protective equipment (PPE) such as gloves and goggles should be worn when working with the compound. Adequate ventilation is essential to avoid inhalation of vapors. Storage conditions for 1-Methylazepane include keeping the container tightly closed in a cool, dry place away from oxidizing agents. The compound should be stored in a flammable liquids cabinet if possible. Spills should be cleaned up immediately using appropriate absorbent materials, and disposal should comply with local regulations.
B2B Procurement Guide
When procuring 1-Methylazepane, B2B buyers should prioritize suppliers who provide high-purity products and comply with safety standards. It is advisable to request certificates of analysis (CoA) to verify the compound's purity and quality. Buyers should also inquire about packaging options to ensure safe transportation and storage. Price ranges for 1-Methylazepane can vary significantly depending on the supplier, quantity, and purity level. Bulk purchases may offer cost savings, but buyers should balance this with storage and handling considerations. Establishing long-term relationships with reliable suppliers can ensure consistent quality and timely delivery.
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