Overview
1-Hexacosanol is a saturated fatty alcohol with a 26-carbon chain, classified as a long-chain primary alcohol. It is naturally found in plant cuticles, beeswax, and sugarcane wax, where it contributes to water resistance and structural integrity. Industrially, it is synthesized via hydrogenation of corresponding fatty acids or through Ziegler alcohol processes. As a high-molecular-weight alcohol, it exhibits unique rheological properties that make it valuable in formulations requiring thickening or textural enhancement. Its biocompatibility and low volatility have led to widespread adoption in personal care products and specialty coatings.
Physical and Chemical Properties
The compound presents as a white, odorless waxy solid at room temperature, with a characteristic high melting point (79-81°C) typical of long-chain aliphatic alcohols. It shows negligible water solubility but dissolves readily in non-polar organic solvents like hexane and moderately in warm ethanol. Chemically, 1-hexacosanol is stable under normal conditions but may undergo esterification with acids or oxidation at elevated temperatures. Its hydroxyl group enables hydrogen bonding, contributing to its crystalline structure and compatibility with other polar compounds in blended formulations.
Main Applications
In cosmetics, 1-hexacosanol serves as an emollient and viscosity modifier in creams, lipsticks, and hair conditioning products. Its ability to form stable crystalline networks improves product texture and provides a non-greasy feel. Pharmaceutical applications include use as an excipient in ointments and sustained-release formulations. Industrial uses encompass wax additives for polishes and coatings, where it enhances hardness and melting properties. Emerging research explores its potential as a bioactive compound in nutraceuticals, with studies suggesting cholesterol-lowering effects at specific dosages.
Safety and Storage
Classified as non-hazardous under GHS criteria, 1-hexacosanol requires standard laboratory precautions—avoid dust formation and eye contact. No significant ecological toxicity has been reported, though biodegradation in aquatic systems may be slow due to its hydrophobic nature. Proper storage involves sealed containers in well-ventilated areas below 30°C. Bulk quantities should be protected from moisture to prevent caking. Shelf life typically exceeds 2 years when stored correctly, with quality verified through melting point and chromatographic analysis if prolonged storage occurs.
B2B Procurement Guide
Industrial buyers should specify purity requirements (cosmetic vs. technical grade), with HPLC analysis recommended for critical applications. Common packaging includes 25kg polyethylene-lined fiber drums or custom quantities for large-scale users. Supplier evaluation should focus on consistency in particle size distribution (affects solubility) and certificates of analysis documenting heavy metal content. Spot purchases typically range $80-120/kg for 99% purity, with volume discounts available above 100kg. Asian and European manufacturers dominate production, with lead times of 2-4 weeks for tailored specifications.
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