1-Bromo-4-(trans-4-butylcyclohexyl)benzene
Overview
1-Bromo-4-(trans-4-butylcyclohexyl)benzene is a brominated aromatic compound with a trans-4-butylcyclohexyl substituent. It serves as a critical building block in the synthesis of advanced liquid crystal materials and pharmaceutical intermediates. The compound's rigid cyclohexyl ring and bromine atom enable precise molecular alignment in liquid crystal mixtures, making it valuable for display technologies. Industrial production typically involves multi-step organic synthesis, starting from 4-butylcyclohexylbenzene. The trans-configuration of the butylcyclohexyl group is particularly important for maintaining the desired mesomorphic properties in end-use applications. Manufacturers often provide technical datasheets specifying isomer purity and residual solvent levels.
Physical and Chemical Properties
The compound exhibits typical characteristics of brominated aromatics with alicyclic substituents. Its crystalline structure and relatively high melting point (85-90°C) make it stable under normal storage conditions. The bromine atom at the para position creates a strong dipole moment, influencing the compound's reactivity in subsequent synthetic steps. Solubility tests show excellent dissolution in common organic solvents like toluene and dichloromethane, but negligible water solubility. This property facilitates its use in organic synthesis while simplifying wastewater management. Thermal gravimetric analysis demonstrates decomposition only above 250°C, confirming suitability for high-temperature liquid crystal applications.
Main Applications
The primary industrial use is as an intermediate in liquid crystal synthesis, particularly for twisted nematic (TN) and in-plane switching (IPS) LCD technologies. Electronics manufacturers value its ability to modify clearing points and reduce rotational viscosity in liquid crystal mixtures. In pharmaceutical R&D, the compound serves as a precursor for cholesterol-lowering drug intermediates. Recent studies also explore its potential in organic light-emitting diodes (OLEDs) as a hole-transport material. Specialty chemical companies often modify the bromine position to create derivatives with tailored properties for niche applications.
Safety and Storage
As a brominated compound, proper handling procedures are essential. Although not classified as acutely toxic, prolonged exposure may cause skin irritation or respiratory sensitization. Laboratories should use fume hoods when handling powders, and industrial facilities require dust control measures. Recommended storage involves amber glass containers or foil-lined bags under nitrogen atmosphere to prevent degradation. Material safety data sheets (MSDS) typically advise keeping the compound away from strong oxidizers and bases. Shelf life generally exceeds two years when stored below 25°C with desiccants.
B2B Procurement Guide
Industrial buyers should prioritize suppliers with ISO-certified production facilities and batch-to-batch consistency guarantees. Key specifications to verify include HPLC purity (≥98%), trans-isomer content (>99%), and residual solvent levels (typically <500 ppm). Bulk procurement (1kg+) often reduces unit costs by 30-50% compared to laboratory-scale quantities. Some manufacturers offer custom bromination services for specific isomer requirements. Logistics planning should account for hazardous material shipping regulations, as air transport may require special permits for brominated compounds.
Related Manufacturers
- 主营：山梨酸钾、羟基嘧啶、吡唑啉酮、磺酸苯基、乙酰苯胺、甲基苯基、清凉茶酸、山梨酸钙、叔丁基锂、双乙烯酮、基氨基锂、氯乙酰氯、三正丁基、四羟甲基、氯羟吡啶、硫酸磷脲
- 主营：冲压油、乙烯基、底涂剂、苯酚cas、cas71-41-0、cas95-50-1、4二碘苯、cas120-82-1、cas106-47-8、cas123-30-8、cas110-87-2、cas110-00-9、cas100-50-5、cas110-82-7、141b清洗剂、cas563-47-3、异构烷烃、甲基乙撑、白色粉末、丙撑二胺、板助焊剂、脱漆剂
- 主营：冲压油、异构烷烃、异构十一烷、反式、医药中间体、清洗剂、缩水甘油醚、农药中间体
- 主营：碘海醇、葡甲胺、氨甲环酸、反式、盐酸柔红霉素、甘油磷酸钠、海藻糖、葡乙胺、古龙酸、托吡酯、潮霉素B、替卡西林钠克拉维酸钾、星孢菌素、盐酸阿霉素、碘帕醇
- 主营：90isoparv、80isoparm、阻燃剂、反式、交联剂、60isoparl、清洗剂、抹机水、底涂剂、活性稀释剂、异构烷烃、乙二醇二缩水甘油醚、聚乙二醇二缩水甘油醚、聚丙二醇二缩水甘油醚、缩水甘油醚、TPGDA、HDDA、TMPTA、DPGDA、三丙二醇二丙烯酸酯、导热油清洗剂
- 主营：胆酸、半叶素、二羟基吲哚、缩合剂、生物缓冲液、表面活性剂、硅烷偶联剂、L-丙交酯、光电材料中间体、精细化工
- 主营：硫酸铯、丹皮酚、有成中、邻氟苯腈、间溴苯腈、二氯苯乙酮、5-二溴苯酚、4'-二溴联苯、邻氯苯甲酰胺、中间体、聚季铵盐、二萘磺酸、硒氰酸钾、仲丁基锂、四乙酸铁、卡非佐米、亚甲基双、萘磺酸二钠、更昔洛韦钠、二胺四乙酸、乙酸二钠盐、酮十一烯酸酯、阿昔洛韦侧链、无机标准物质、5-三氯吡啶
- 主营：氯化偏苯三酸酐、N-二甲基烯丙基
- 主营：--
- 主营：--
- 主营：植物醇、植物提取物、8-二氨基萘、4-辛氧基二苯碘六氟、4-萘二甲酸、8-氨基喹哪啶、聚二羟基吲哚、2-巯基噻唑啉、6-二羟基吲哚氢、磷钼酸、石胆酸、乙烯基膦酸、劳伦酸、二水合钼酸钠、麦角硫因、DL-樟脑醌、羟乙基磺酸、钼酸、甲基丙烯酸氧杂环丁烷、三羟甲基氨基甲烷盐酸、4-羟乙基哌嗪乙磺酸、5-甲基 N-乙烯基、腺苷、L-谷氨酸-5-叔丁、聚季铵盐-55
- 主营：甘氨酰、碳酸镁、特戊醛、二苯胍、化合物、碲化钠
- 主营：恩布酯、甘氨酰、4282-24-0、1692-15-5、二苯胺、1897-45-6、7681-52-9、1776-30-3、1317-80-2、1069-23-4、氟苯基、7779-90-0、聚合物、6809-52-5、嘧菌酯、磷酸铬、褪黑素、3486-30-4、5856-62-2、吡咯基、达比加、异戊醛、化合物、碲化钠、氟洛芬