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Updated: 2026-07-19

Overview

1-(3-Chlorophenyl)piperazine, commonly abbreviated as mCPP, is a chemical compound that belongs to the phenylpiperazine class. It is primarily used in pharmaceutical research and biochemical studies due to its activity as a serotonin receptor agonist. The compound is known for its role in studying neurotransmitter systems and has been investigated for various pharmacological effects. Its molecular structure includes a chlorophenyl group attached to a piperazine ring, which contributes to its biological activity.

Physical and Chemical Properties

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1-(3-Chlorophenyl)piperazine appears as a white to off-white crystalline powder with a melting point of approximately 100-102°C. It is soluble in organic solvents such as ethanol and methanol, but its solubility in water is limited. The compound's stability is influenced by storage conditions. It should be kept in a cool, dry environment to prevent degradation. Its molecular weight is 196.68 g/mol, and its structure includes a chlorine atom, which affects its reactivity and interactions.

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Main Applications

The primary application of 1-(3-Chlorophenyl)piperazine is in pharmaceutical research, where it is used to study serotonin receptors and their effects on the central nervous system. It serves as a tool compound in biochemical assays. Additionally, mCPP has been explored in the development of potential therapeutic agents for conditions related to neurotransmitter imbalances. Its use is strictly limited to research settings, and it is not approved for medical or consumer applications.

Safety and Storage

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When handling 1-(3-Chlorophenyl)piperazine, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound may cause irritation to the skin, eyes, and respiratory system upon exposure. Storage should be in a tightly sealed container, away from light, moisture, and extreme temperatures. Proper labeling and adherence to local regulations for hazardous chemicals are crucial to ensure safe handling and disposal.

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B2B Procurement Guide

B2B buyers seeking 1-(3-Chlorophenyl)piperazine should prioritize suppliers with verified credentials and compliance with regulatory standards. It is important to request certificates of analysis (CoA) to ensure product purity and quality. Procurement should also consider the intended use, as regulatory restrictions may apply depending on the region. Bulk purchases may offer cost advantages, but buyers should confirm storage and handling requirements to maintain product integrity.

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